The best Side of cees dekker
The best Side of cees dekker
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Nanotechnology offers a range of options to lead to biology. Below I'll existing examples exactly where nanofabrication – the chance to make confined constructions with dimensions at will – is utilised to look at the biophysics of solitary molecules and cells. I'll current some examples from our lab:
Reconstitution of ultrawide DNA origami pores in liposomes for transmembrane transport of macromolecules
‘It absolutely was just a make any difference of choosing up a e book on cell biology and starting to examine. I had come from a earth of extremely-large vacuums, cryostats and quantum phenomena, and now I used to be working at space temperature with molecular biology kits.
Our function was swiftly followed up by Other individuals, most notably by Phaedon Avouris and colleagues at IBM, who in October 1998 revealed their results on transistors made out of single- and multi-walled carbon nanotubes in Used Physics Letters.
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Illustration (3) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is demonstrated in grey, the rim with the pore is highlighted in crimson, along with a 3D rendering of your motion from the DNA rod is exhibited.
We form microorganisms into types that deviate from their all-natural phenotype. Particularly, I'll clearly show our capacity to form Reside E. coli bacteria into novel styles such as rectangles, squares, triangles and circles.
Instance (one) of bending ceesdekker configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is revealed in grey, the rim of your pore is highlighted in crimson, and a 3D rendering on the motion on the DNA rod is displayed.
In 1993, like a youthful and eager associate professor at Delft University of Technological innovation, I'd originally centered the research attempts of my group on measuring the electrical conductance of only one conducting-polymer molecule. Within two a long time, we experienced established a device during which an individual wire of the phthalocyaninepolysiloxane polymer was related in between two intently spaced steel nanoelectrodes.
It was in the course of this period that Dekker completed exploration on magnetic spin units and on noise in superconductors and semiconductors.
Screening pseudotopological and nontopological models for SMC-driven DNA loop extrusion from roadblock-traversal experiments
Nanoscientist Cees Dekker is definitely an amiable and flamboyant man who seems Substantially youthful compared to 62 years he basically is – stylish glasses, psychedelic shirt, engaging smile – although not a person to squander time. He usually takes his time, but not more than essential.
2008, initially observation of protein-coated DNA translocation by nanopores; fixed the origin with the electrophoretic pressure on DNA in nanopores; learned a big velocity maximize of microtubules in electric powered fields; learned an anomalous electro-hydrodynamic orientation of microtubules; and solved the origin of sound in carbon nanotubes in liquid
2013, managed shaping of Dwell bacterial cells into arbitrary styles; and discovery of spontaneous fluctuations inside the handedness of histone tetrasomes